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[광우병] 2012 프리온 학회(암스테르담) 프로그램


























































































































































































































http://prion2012.com/program/final-program

Wednesday May 9, 2012

Time Session Speakers Chair persons Room
12:00 – 20.00  Registration open
13:00 – 18:00 Natural TSEs in Animals workshop Aula
18:00 – 20.00  Welcome Reception  Foyer


Thursday May 10, 2012

Time Session Speakers Chair persons Room
07:30 – 18.00  Registration open
08:30 – 08:50  Opening Ceremony  Langeveld   Aula 
08:50 – 09:40 Plenary Lecture PLEN1: Prion propagation and its wider implications Collinge Langeveld / Deslys Aula 
09:40 – 10:10 PrPSc structure & nature of the agent Surewicz Langeveld / Deslys Aula 
10:10 – 10:40 Break     Foyer
10:40 – 12:00 PrPSc structure & nature of the agent Somerville, Wille, Starck, Lührs Requena / Torres Aula 
12:00 – 14:00 Lunch & Poster Sessions      Foyer
14.00 – 16.00 Transmission & Strains Beringue, Van Keulen, Saa, David, Nonno, Kloehn Agrimi / Bossers Aula 
16:00 – 16:30 Break     Foyer
16:30 – 17:25 Pathogenesis & Pathology  Hoover, Mallucci, Godsave  Jeffrey / De Koeijer Aula 
17:25 – 18:20 Epidemiology & risk analysis Van Duijn, Comer, Sala Jeffrey / De Koeijer Aula 
19:00 Departure Social Event  VU
19:30 – 24:00 Social Event 


Friday May 11, 2012

Time Session Speakers Chair persons Room
08:00 – 18.00  Registration open
08:30 – 09:20 Plenary Lecture PLEN2: Mechanisms of neurotoxicity in prion infections Aguzzi Rozemuller / Gambetti Aula 
09:20 – 10:30 Protein folding diseases Dobson, Jeffrey, Shorter Rozemuller / Gambetti Aula 
10:30 – 11:00 Break     Foyer
11:00 – 12:20 Diagnosis & therapeutics Caughey, Cashman, Schatzl, Nyström Sklaviadis / Pocchiari Aula 
12:20 – 14:20 Lunch & Poster Sessions      Foyer
14.20 – 15.25 Susceptibility & genetics Agrimi, Bossers, Stepanova Baron / Schatzl  Aula 
15:25 – 16:25  PrP biology & function Tatzelt, Radfort, Westaway Baron / Schatzl  Aula 
16:25 – 16:55 Break     Foyer
16:55 – 17:20 Patients and patient organisation(s) Solvyns, Kranitz  Langeveld / Deslys Aula 
17:20 – 18:30 Human prion diseases Gambetti, Rozemuller, Kovacs Budka / Veerhuis Aula 
18:30 Free evening 


Saturday May 12, 2012

Time Session Speakers Chair persons Room
08:00 – 12:00  Registration open
08:30 – 09:20 Blood safety, decontamination, environment Will, Simoneau, Comoy Brown / Deslys Aula 
09:20 – 10:00 Poster Award Winners Ceremony To be announced on site Poster Jury  Aula 
10:00 – 10:30 Break     Foyer
10:30 – 11:50 Hot Topics  Van Nostrand, Baskakov, Castilla, Baron, Zou
Manson / Tagliavini  Aula 
11:50 – 12:00 Closing ceremony Langeveld   Aula 
12:00 End conference / next conference / departure


 


Sessions







































































































Thursday May 10, 2012  09h40 – 18h20

Session: PrPSc structure & nature of the agent   Chair persons: Langeveld, Deslys, Requena, Torres
OR-01 09:40 – 10:10 THE CHALLENGE OF STRUCTURAL UNDERSTANDING OF PRION PROTEIN CONVERSION AND PRION PROPAGATION Surewicz
OR-02 10:40 – 11:05 INTRINSIC STRUCTURAL AND FUNCTIONAL PROPERTIES OF EXPERIMENTAL TSE STRAINS Somerville
OR-03 11:05 – 11:25 A COMPACT, FOUR-STRANDED BETA-SHEET CORE IS FOUND IN PRIONS FROM ALL NATURAL PRION ISOLATES AND SYNTHETIC PRION STRAINS ANALYZED Wille
OR-04 11:25 – 11:40 STRUCTURE AND DYNAMICS OF A TOXIC SYRIAN HAMSTER PRION PROTEIN BETA-INTERMEDIATE Starck 
OR-05 11:40 – 12:00 CONFORMATION SELECTIVE PRION AMPLIFICATION USING SPECIFIC SHEAR FIELDS Lührs
Session: Transmission & Strains  Chair persons:
Agrimi, Bossers
OR-06 14:00 – 14:30 PRION DIVERSITY AND EVOLUTION: WHAT ANIMAL STRAIN TYPING TELLS US  Beringue
OR-07 14:30 – 14:55 PRPSC PROFILES IN TSE STRAINTYPING  Van Keulen
OR-08 14:55 – 15:10 STRAIN–SPECIFIC ROLE OF RNAS IN PRION REPLICATION Saa
OR-09 15:10 – 15:25 CANINE SPONGIFORM ENCEPHALOPATHY: A NEW FORM OF ANIMAL PRION DISEASE David
OR-10 15:25 – 15:40 VARIABLY PROTEASE-SENSITIVE PRIONOPATHY IS TRANSMISSIBLE IN BANK VOLES Nonno
OR-11 15:40 – 16:00 PLASMACYTOID DENDRITIC CELLS SEQUESTER HIGH PRION TITRES AT EARLY STAGES OF PRION INFECTION Kloehn 
Session: Pathogenesis & Pathology  Chair persons:
Jeffrey, De Koeijer
OR-12 16:30 – 16:55 PRION DIVERSITY AND EVOLUTION: WHAT ANIMAL STRAIN TYPING TELLS US  Hoover
OR-13 16:55 – 17:10 SUSTAINED TRANSLATIONAL REPRESSION BY EIF2alpha-P MEDIATES PRION NEURODEGENERATION Malluci 
OR-14 17:10 – 17:25 EARLY PLASMA MEMBRANE ACCUMULATIONS OF NASCENT PRIONS IN HIPPOCAMPUS; POSSIBLE SITES OF REPLICATION, CELL-TO CELL TRANSFER AND PATHOLOGY Godsave
Session: Epidemiology & risk analysis Chair persons:
Jeffrey, De Koeijer 
OR-15 17:25 – 17:50 ADVANCES IN THE GENETIC EPIDEMIOLOGY OF CREUTZFELDT-JAKOB DISEASE AND RELATED DISEASES  Van Duijn 
OR-16 17:50 – 18:05 A COST EFFECTIVENESS STUDY OF THE USE OF ANTE-MORTEM TSE TESTS ON CATTLE IN THE UK Comer
OR-17 18:05 – 18:20 OLD CATTLE AND THE RISK OF ATYPICAL BOVINE SPONGIFORM ENCEPHALOPATHY Sala 


 





































































































Friday May 11, 2012  09h20 – 18h30

Session: Protein folding diseases Chair persons: Rozemuller, Gambetti 
OR-18 09:20 – 09:50 THE NATURE AND SIGNIFICANCE OF PROTEIN AGGREGATION PHENOMENA Dobson
OR-19 09:50 – 10:15 SYNTHETIC PRP RELATED DISORDERS AND NATURAL TSES SHARE DISEASE ASSOCIATED PRP MEMBRANCE ACCUMULATION  Jeffrey
OR-20 10:15 – 10:30 RNA-BINDING PROTEINS WITH PRION-LIKE DOMAINS IN ALS AND BEYOND Shorter
Session: Diagnosis & therapeutics Chair persons: Kretzschmar, Pocchiari
OR-21 11:00 – 11:30 PRION-SEEDED CONVERSION OF RECOMBINANT PRP: IMPLICATIONS FOR PRION BIOLOGY AND DIAGNOSTICS Caughey
OR-22 11:30 – 11:50 PROPAGATED MISFOLDING OF SOD1 IN ALS Cashman
OR-23 11:50 – 12:05 ELUCIDATING THE CELLULAR MECHANISMS OF PRION PROPAGATION AND CLEARANCE FOR DEVISING NEW TARGETS FOR INTERVENTION Schatzl 
OR-24 12:05 – 12:20 MONITORING AMYLOID FORMATION AND MATURATION IN VITRO AND IN VIVO USING LCO FLUORESCENCE Nyström
Session: Susceptibility & genetics Chair persons:
Baron, Schatzl 
OR-25 14:20 – 14:45 PRNP AND SUSCEPTIBILITY TO PRION DISEASES: FROM RESISTANCE TO SPONTANEOUS DISEASE Agrimi 
OR-26 14:45 – 15:10 MOLECULAR ASSESSMENT OF RUMINANT SUSCEPTIBILITY FOR VARIOUS TSE SOURCES Bossers
OR-27 15:10 – 15:25 COMPARATIVE ANALYSIS OF PRION PROTEINS FOR EVOLUTIONARILY DIVERSE VERTEBRAE SPECIES, POLYMORPHIC VARIANTS AND MUTANTS: STRUCTURE AND ESSENTIAL DYNAMICS Stepanova
Session: PrP biology & function Chair persons:
Baron, Schaltz
OR-28 15:25 – 15:50 THE CELLULAR PRION PROTEIN MEDIATES NEUROTOXIC SIGNALING OF SCRAPIE PRIONS AND AB Tatzelt
OR-29 15:50 – 16:05 THE ROLE OF PRP IN SYNAPTIC FUNCTION AND REPAIR: IMPLICATIONS FOR TREATMENT OF PRION AND ALZHEIMER’S DISEASES Radfort
OR-30 16:05 – 16:25 PROPERTIES OF GEOMETRY-LOCKED PRPS AND SHADOO PROTEIN IN HEALTH AND DISEASE  Westaway
Session: Human prion diseases Chair persons:
Budka, Veerhuis
OR-31 17:20 – 17:50 PRION STRAINS IN HUMAN PRION DISEASES: VARIABLY PROTEASE-SENSITIVE PRIONOPATHTY COMPARED WITH OTHER Gambetti
OR-32 17:50 – 18:15 HUMAN PRION DISEASES IN THE NETHERLANDS (1998-2009): CLINICAL, GENETIC AND MOLECULAR ASPECTS  Rozemuller
OR-33 18:15 – 18:30 THALAMIC DEGENERATION CLINICALLY PRESENTING AS CJD: MORE FREQUENT THAN ASSUMED? Kovacs


 




















































Saturday May 12, 2012  08h30 – 12h00

Session: Blood safety, decontamination, environment Chair persons:
Brown, Deslys
OR-34 08:30 – 08:50 AN UPDATE OF TRANSFUSION TRANSMISSION OF VARIANT CREUTZFELDT-JAKOB DISEASE (VCJD) Will 
OR-35 08:50 – 09:05 EFFICACY OF ETHANOL PRECIPITATION (TI+III + TII) AND NANOFILTRATION IN REMOVAL OF A HIGH SPEED PURIFIED NON SEDIMENTABLE PRION SPIKE Simoneau 
OR-36 09:05 – 09:20 A NEW NEUROLOGICAL DISEASE IN PRIMATES INOCULATED WITH PRION-INFECTED BLOOD OR BLOOD COMPONENTS Comoy
Session: Hot topics     Chair persons:
Manson, Tagliavini
OR-37 10:30 – 10:50 CONDITIONAL CROSS SEEDING OF NORMAL AND VASCULOTROPIC MUTANT AMYLOID B-PROTEIN IN TRANSGENIC MICE Van Nostrand
OR-38 10:50 – 11:05 GENESIS OF MAMMALIAN PRIONS Baskakov
OR-39 11:05 – 11:20 HIGHLY INFECTIOUS RECOMBINANT PRIONS: A NEW CHALLENGE FOR UNDERSTANDING HOW PRIONS WORK Castilla
OR-40 11:20 – 11:35 PRION-LIKE ACCELERATION OF A SYNUCLEINOPATHY IN A TRANSGENIC MOUSE MODEL Baron 
OR-41 11:35 – 11:50 RIONS LACKING GLYCOSYLATED PRP AT THE FIRST N-GLYCOSYLATION SITE IN BOTH VARIABLY PROTEASE-SENSITIVE PRIONOPATHY AND A FAMILIAL PRION DISEASE

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