http://prion2012.com/program/final-program | ||||
Time | Session | Speakers | Chair persons | Room |
12:00 – 20.00 | Registration open | |||
13:00 – 18:00 | Natural TSEs in Animals workshop | Aula | ||
18:00 – 20.00 | Welcome Reception | Foyer | ||
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Time | Session | Speakers | Chair persons | Room |
07:30 – 18.00 | Registration open | |||
08:30 – 08:50 | Opening Ceremony | Langeveld | Aula | |
08:50 – 09:40 | Plenary Lecture PLEN1: Prion propagation and its wider implications | Collinge | Langeveld / Deslys | Aula |
09:40 – 10:10 | PrPSc structure & nature of the agent | Surewicz | Langeveld / Deslys | Aula |
10:10 – 10:40 | Break | Foyer | ||
10:40 – 12:00 | PrPSc structure & nature of the agent | Somerville, Wille, Starck, Lührs | Requena / Torres | Aula |
12:00 – 14:00 | Lunch & Poster Sessions | Foyer | ||
14.00 – 16.00 | Transmission & Strains | Beringue, Van Keulen, Saa, David, Nonno, Kloehn | Agrimi / Bossers | Aula |
16:00 – 16:30 | Break | Foyer | ||
16:30 – 17:25 | Pathogenesis & Pathology | Hoover, Mallucci, Godsave | Jeffrey / De Koeijer | Aula |
17:25 – 18:20 | Epidemiology & risk analysis | Van Duijn, Comer, Sala | Jeffrey / De Koeijer | Aula |
19:00 | Departure Social Event | VU | ||
19:30 – 24:00 | Social Event | |||
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Time | Session | Speakers | Chair persons | Room |
08:00 – 18.00 | Registration open | |||
08:30 – 09:20 | Plenary Lecture PLEN2: Mechanisms of neurotoxicity in prion infections | Aguzzi | Rozemuller / Gambetti | Aula |
09:20 – 10:30 | Protein folding diseases | Dobson, Jeffrey, Shorter | Rozemuller / Gambetti | Aula |
10:30 – 11:00 | Break | Foyer | ||
11:00 – 12:20 | Diagnosis & therapeutics | Caughey, Cashman, Schatzl, Nyström | Sklaviadis / Pocchiari | Aula |
12:20 – 14:20 | Lunch & Poster Sessions | Foyer | ||
14.20 – 15.25 | Susceptibility & genetics | Agrimi, Bossers, Stepanova | Baron / Schatzl | Aula |
15:25 – 16:25 | PrP biology & function | Tatzelt, Radfort, Westaway | Baron / Schatzl | Aula |
16:25 – 16:55 | Break | Foyer | ||
16:55 – 17:20 | Patients and patient organisation(s) | Solvyns, Kranitz | Langeveld / Deslys | Aula |
17:20 – 18:30 | Human prion diseases | Gambetti, Rozemuller, Kovacs | Budka / Veerhuis | Aula |
18:30 | Free evening | |||
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Time | Session | Speakers | Chair persons | Room |
08:00 – 12:00 | Registration open | |||
08:30 – 09:20 | Blood safety, decontamination, environment | Will, Simoneau, Comoy | Brown / Deslys | Aula |
09:20 – 10:00 | Poster Award Winners Ceremony | To be announced on site | Poster Jury | Aula |
10:00 – 10:30 | Break | Foyer | ||
10:30 – 11:50 | Hot Topics | Van Nostrand, Baskakov, Castilla, Baron, Zou | Manson / Tagliavini | Aula |
11:50 – 12:00 | Closing ceremony | Langeveld | Aula | |
12:00 | End conference / next conference / departure |
Sessions
Thursday May 10, 2012 09h40 – 18h20 | |||
Session: PrPSc structure & nature of the agent | Chair persons: Langeveld, Deslys, Requena, Torres | ||
OR-01 | 09:40 – 10:10 | THE CHALLENGE OF STRUCTURAL UNDERSTANDING OF PRION PROTEIN CONVERSION AND PRION PROPAGATION | Surewicz |
OR-02 | 10:40 – 11:05 | INTRINSIC STRUCTURAL AND FUNCTIONAL PROPERTIES OF EXPERIMENTAL TSE STRAINS | Somerville |
OR-03 | 11:05 – 11:25 | A COMPACT, FOUR-STRANDED BETA-SHEET CORE IS FOUND IN PRIONS FROM ALL NATURAL PRION ISOLATES AND SYNTHETIC PRION STRAINS ANALYZED | Wille |
OR-04 | 11:25 – 11:40 | STRUCTURE AND DYNAMICS OF A TOXIC SYRIAN HAMSTER PRION PROTEIN BETA-INTERMEDIATE | Starck |
OR-05 | 11:40 – 12:00 | CONFORMATION SELECTIVE PRION AMPLIFICATION USING SPECIFIC SHEAR FIELDS | Lührs |
Session: Transmission & Strains | Chair persons: Agrimi, Bossers | ||
OR-06 | 14:00 – 14:30 | PRION DIVERSITY AND EVOLUTION: WHAT ANIMAL STRAIN TYPING TELLS US | Beringue |
OR-07 | 14:30 – 14:55 | PRPSC PROFILES IN TSE STRAINTYPING | Van Keulen |
OR-08 | 14:55 – 15:10 | STRAIN–SPECIFIC ROLE OF RNAS IN PRION REPLICATION | Saa |
OR-09 | 15:10 – 15:25 | CANINE SPONGIFORM ENCEPHALOPATHY: A NEW FORM OF ANIMAL PRION DISEASE | David |
OR-10 | 15:25 – 15:40 | VARIABLY PROTEASE-SENSITIVE PRIONOPATHY IS TRANSMISSIBLE IN BANK VOLES | Nonno |
OR-11 | 15:40 – 16:00 | PLASMACYTOID DENDRITIC CELLS SEQUESTER HIGH PRION TITRES AT EARLY STAGES OF PRION INFECTION | Kloehn |
Session: Pathogenesis & Pathology | Chair persons: Jeffrey, De Koeijer | ||
OR-12 | 16:30 – 16:55 | PRION DIVERSITY AND EVOLUTION: WHAT ANIMAL STRAIN TYPING TELLS US | Hoover |
OR-13 | 16:55 – 17:10 | SUSTAINED TRANSLATIONAL REPRESSION BY EIF2alpha-P MEDIATES PRION NEURODEGENERATION | Malluci |
OR-14 | 17:10 – 17:25 | EARLY PLASMA MEMBRANE ACCUMULATIONS OF NASCENT PRIONS IN HIPPOCAMPUS; POSSIBLE SITES OF REPLICATION, CELL-TO CELL TRANSFER AND PATHOLOGY | Godsave |
Session: Epidemiology & risk analysis | Chair persons: Jeffrey, De Koeijer | ||
OR-15 | 17:25 – 17:50 | ADVANCES IN THE GENETIC EPIDEMIOLOGY OF CREUTZFELDT-JAKOB DISEASE AND RELATED DISEASES | Van Duijn |
OR-16 | 17:50 – 18:05 | A COST EFFECTIVENESS STUDY OF THE USE OF ANTE-MORTEM TSE TESTS ON CATTLE IN THE UK | Comer |
OR-17 | 18:05 – 18:20 | OLD CATTLE AND THE RISK OF ATYPICAL BOVINE SPONGIFORM ENCEPHALOPATHY | Sala |
Friday May 11, 2012 09h20 – 18h30 | |||
Session: Protein folding diseases | Chair persons: Rozemuller, Gambetti | ||
OR-18 | 09:20 – 09:50 | THE NATURE AND SIGNIFICANCE OF PROTEIN AGGREGATION PHENOMENA | Dobson |
OR-19 | 09:50 – 10:15 | SYNTHETIC PRP RELATED DISORDERS AND NATURAL TSES SHARE DISEASE ASSOCIATED PRP MEMBRANCE ACCUMULATION | Jeffrey |
OR-20 | 10:15 – 10:30 | RNA-BINDING PROTEINS WITH PRION-LIKE DOMAINS IN ALS AND BEYOND | Shorter |
Session: Diagnosis & therapeutics | Chair persons: Kretzschmar, Pocchiari | ||
OR-21 | 11:00 – 11:30 | PRION-SEEDED CONVERSION OF RECOMBINANT PRP: IMPLICATIONS FOR PRION BIOLOGY AND DIAGNOSTICS | Caughey |
OR-22 | 11:30 – 11:50 | PROPAGATED MISFOLDING OF SOD1 IN ALS | Cashman |
OR-23 | 11:50 – 12:05 | ELUCIDATING THE CELLULAR MECHANISMS OF PRION PROPAGATION AND CLEARANCE FOR DEVISING NEW TARGETS FOR INTERVENTION | Schatzl |
OR-24 | 12:05 – 12:20 | MONITORING AMYLOID FORMATION AND MATURATION IN VITRO AND IN VIVO USING LCO FLUORESCENCE | Nyström |
Session: Susceptibility & genetics | Chair persons: Baron, Schatzl | ||
OR-25 | 14:20 – 14:45 | PRNP AND SUSCEPTIBILITY TO PRION DISEASES: FROM RESISTANCE TO SPONTANEOUS DISEASE | Agrimi |
OR-26 | 14:45 – 15:10 | MOLECULAR ASSESSMENT OF RUMINANT SUSCEPTIBILITY FOR VARIOUS TSE SOURCES | Bossers |
OR-27 | 15:10 – 15:25 | COMPARATIVE ANALYSIS OF PRION PROTEINS FOR EVOLUTIONARILY DIVERSE VERTEBRAE SPECIES, POLYMORPHIC VARIANTS AND MUTANTS: STRUCTURE AND ESSENTIAL DYNAMICS | Stepanova |
Session: PrP biology & function | Chair persons: Baron, Schaltz | ||
OR-28 | 15:25 – 15:50 | THE CELLULAR PRION PROTEIN MEDIATES NEUROTOXIC SIGNALING OF SCRAPIE PRIONS AND AB | Tatzelt |
OR-29 | 15:50 – 16:05 | THE ROLE OF PRP IN SYNAPTIC FUNCTION AND REPAIR: IMPLICATIONS FOR TREATMENT OF PRION AND ALZHEIMER’S DISEASES | Radfort |
OR-30 | 16:05 – 16:25 | PROPERTIES OF GEOMETRY-LOCKED PRPS AND SHADOO PROTEIN IN HEALTH AND DISEASE | Westaway |
Session: Human prion diseases | Chair persons: Budka, Veerhuis | ||
OR-31 | 17:20 – 17:50 | PRION STRAINS IN HUMAN PRION DISEASES: VARIABLY PROTEASE-SENSITIVE PRIONOPATHTY COMPARED WITH OTHER | Gambetti |
OR-32 | 17:50 – 18:15 | HUMAN PRION DISEASES IN THE NETHERLANDS (1998-2009): CLINICAL, GENETIC AND MOLECULAR ASPECTS | Rozemuller |
OR-33 | 18:15 – 18:30 | THALAMIC DEGENERATION CLINICALLY PRESENTING AS CJD: MORE FREQUENT THAN ASSUMED? | Kovacs |
Saturday May 12, 2012 08h30 – 12h00 | |||
Session: Blood safety, decontamination, environment | Chair persons: Brown, Deslys | ||
OR-34 | 08:30 – 08:50 | AN UPDATE OF TRANSFUSION TRANSMISSION OF VARIANT CREUTZFELDT-JAKOB DISEASE (VCJD) | Will |
OR-35 | 08:50 – 09:05 | EFFICACY OF ETHANOL PRECIPITATION (TI+III + TII) AND NANOFILTRATION IN REMOVAL OF A HIGH SPEED PURIFIED NON SEDIMENTABLE PRION SPIKE | Simoneau |
OR-36 | 09:05 – 09:20 | A NEW NEUROLOGICAL DISEASE IN PRIMATES INOCULATED WITH PRION-INFECTED BLOOD OR BLOOD COMPONENTS | Comoy |
Session: Hot topics | Chair persons: Manson, Tagliavini | ||
OR-37 | 10:30 – 10:50 | CONDITIONAL CROSS SEEDING OF NORMAL AND VASCULOTROPIC MUTANT AMYLOID B-PROTEIN IN TRANSGENIC MICE | Van Nostrand |
OR-38 | 10:50 – 11:05 | GENESIS OF MAMMALIAN PRIONS | Baskakov |
OR-39 | 11:05 – 11:20 | HIGHLY INFECTIOUS RECOMBINANT PRIONS: A NEW CHALLENGE FOR UNDERSTANDING HOW PRIONS WORK | Castilla |
OR-40 | 11:20 – 11:35 | PRION-LIKE ACCELERATION OF A SYNUCLEINOPATHY IN A TRANSGENIC MOUSE MODEL | Baron |
OR-41 | 11:35 – 11:50 | RIONS LACKING GLYCOSYLATED PRP AT THE FIRST N-GLYCOSYLATION SITE IN BOTH VARIABLY PROTEASE-SENSITIVE PRIONOPATHY AND A FAMILIAL PRION DISEASE |